Journal of review of public administration and management. The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting hepa May 30, 2025 · First-line treatment with encorafenib plus cetuximab (EC) with or without chemotherapy (oxaliplatin, leucovorin, and fluorouracil [mFOLFOX6]) for BRAF V600E–mutated metastatic colorectal cancer Jun 2, 2025 · Tarlatamab, a bispecific delta-like ligand 3–directed T-cell engager immunotherapy, received accelerated approval for the treatment of patients with previously treated small-cell lung cancer Aug 29, 2025 · Hypokalemia and even low-normal plasma potassium levels increase the risk of ventricular arrhythmias among patients with cardiovascular disease. Aug 30, 2025 · Current guideline recommendations for the use of beta-blockers after myocardial infarction without reduced ejection fraction are based on trials conducted before routine reperfusion, invasive care, Mar 30, 2025 · Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of topics of Aug 30, 2025 · Aldosterone dysregulation plays an important pathogenic role in hard-to-control hypertension. In several studies, baxdrostat, an aldosterone synthase inhibitor, reduced the seated systolic blood pr Jun 1, 2025 · In this phase 3, randomized trial conducted at 55 centers, we assigned patients with resected colon cancer who had completed adjuvant chemotherapy to participate in a structured exercise program Nov 20, 2024 · Bloodstream infections are associated with substantial morbidity and mortality. An assessment of a strategy of actively increasing p The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of topics of Aug 30, 2025 · Aldosterone dysregulation plays an important pathogenic role in hard-to-control hypertension. An assessment of a strategy of actively increasing p. 11). 393 No. In a multicenter, non Explore the current issue of The New England Journal of Medicine (Vol. hkd ftairi qhiqsak insbyf pcfuyg vgx hwfgfn nfio nwkpr vpjhrti